郭昌 - 中国科学技术大学 - 合肥微尺度物质科学国家研究中心

个人简介

2018.03 - 至今特任教授，博士生导师，合肥微尺度物质科学国家研究中心 2017.02-2018.02 特任研究员，中国科学技术大学，合肥微尺度物质科学国家研究中心 2013.08-2017.01 博士后，德国明斯特大学 2007.09-2013.06 博士，中国科学技术大学 2003.08-2007.06 学士，中国科学技术大学

研究领域

研究工作主要集中在不对称合成方向，以新型不对称催化研究为基础，发展惰性化学键的直接手性官能团化反应，建立手性催化模型，提高反应活性与选择性，并将这些方法学用于天然产物的合成，发展高效、原子经济性和环境友好的现代有机合成化学。

近期论文

查看导师新发文章（温馨提示：请注意重名现象，建议点开原文通过作者单位确认）

1. Wang, H.; Guo, C.* Enantioselective γ‐Addition of Pyrazole and Imidazole Heterocycles to Allenoates Catalyzed by Chiral Phosphine. Angew. Chem. Int. Ed. 2019, 58, 2854-2858. 2. Chang, X.; Zhang, Q.; Guo. C.* Electrochemical Reductive Smiles Rearrangement for C−N Bond Formation. Org. Lett. 2019, 21, 10-13. 3. Guo, C.*; Janssen-Müller, D.; Fleige, M.;Lerchen, A.; Daniliuc, C. G.; Glorius, F.* Mechanistic studies on a cooperative NHC organocatalysis/palladium catalysis system: uncovering significant lessons for mixed chiral Pd(NHC)(PR3) catalyst design. J. Am. Chem. Soc. 2017, 139, 4443-4451. 4. Guo, C.; Fleige, M.; Janssen-Müller, D.; Daniliuc, C. G.; Glorius, F.* Cooperative N-heterocyclic carbene/palladium-catalyzed enantioselective umpolungannulations, J. Am. Chem. Soc. 2016, 138, 7840-7843. 5. Guo, C.; Fleige, M.; Janssen-Müller, D.; Daniliuc, C. G.; Glorius, F. *Switchable selectivity in an NHC-catalyseddearomatizing annulation reaction, Nat. Chem. 2015, 7, 842-847. 6. Guo,C.;Sahoo, B.;Daniliuc,C. G.;Glorius,F.*N-Heterocyclic carbenecatalyzed switchable reactions of enals with azoalkenes: formal [4+3] and [4+1] annulations for the synthesis of 1,2-diazepines and pyrazoles, J. Am. Chem. Soc. 2014, 136,17402-17405. 7. Guo, C.;Schedler, M.;Daniliuc, C. G.;Glorius,F.*N-Heterocyclic carbenecatalyzed formal [3+2] annulation reaction of enals: an efficient enantioselective access to spiro-heterocycles, Angew. Chem. Int. Ed. 2014, 53, 10232-10236. 8. Guo, C.; Song, J.; Huang, J.-Z.; Chen, P.-H.; Luo, S.-W.; Gong, L.-Z. *Core-structure-oriented asymmetric organocatalyticsubstitution of3-hydroxyoxindoles: application in the enantioselective total synthesis of (+)-folicanthine. Angew. Chem. Int. Ed. 2012, 51, 1046-1050. 9. Guo, C.; Song, J.; Luo, S.-W.; Gong, L.-Z. *Enantioselective oxidative cross-coupling reaction of 3-indolylmethyl C-H bonds with 1,3-dicarbonyls using a chiral Lewis acid-bonded nucleophile to control stereochemistry. Angew. Chem. Int. Ed. 2010, 49, 5558-5562. 10. Guo, C.; Xue, M.-X.; Zhu, M.-K.; Gong, L.-Z.* Organocatalytic asymmetric formal [3+2] cycloaddition reaction of iocyanoesters to nitroolefinsleading to highly optically active dihydropyrroles. Angew. Chem. Int. Ed. 2008, 47, 3414-3417.