个人简介
Jianqin Lu, BPharm, PhD, Assistant Professor of Pharmaceutical Sciences in Pharmaceutics and Pharmacokinetics, Department of Pharmacology and Toxicology.
The overarching goal of the Lu lab is to apply synthetic chemistry, nanoparticle engineering, and tumor immunology to develop efficacious nanotherapeutics to address the pressing unmet needs in current cancer therapy. The Lu Lab's expertise in Pharmaceutics, Drug Delivery, Nanomedicine and Tumor Immunology paves the way to develop transformative and clinically translatable nano-enabled immunotherapeutics for combatting cancers.
Post-Doctoral, Nanomedicine/Tumor Immunology, University of California, Los Angeles 2019
Post-Doctoral, Nanomedicine, The University of Chicago, 2015
PhD, Pharmaceutics, University of Pittsburgh, 2014
BS, Pharmacy, Hunan University of Chinese Medicine (China), 2010
研究领域
Drug Delivery
Nanomedicine
Pharmaceutics and Pharmacokinetics
Nano-ImmunoEngineering
Cancer Immunotherapy and Chemotherapy
Biomaterials
近期论文
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Lu, J., X. Liu, Y-P. Liao, X. Wang, A. Ahmed, W. Jiang, Y. Ji, H. Meng, and A. E. Nel, "Breast Cancer Chemo-immunotherapy through Liposomal Delivery of an Immunogenic Cell Death Stimulus Plus Interference in the IDO-1 Pathway.", ACS Nano, vol. 12, issue 11, pp. 11041-11061, 2018 Nov 27. PMCID: PMC6262474 PMID: 30481959
Lu, J., X. Liu, Y-P. Liao, F. Salazar, B. Sun, W. Jiang, C. Hyun Chang, J. Jiang, X. Wang, A. M. Wu, et al., "Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression.", Nat Commun, vol. 8, issue 1, pp. 1811, 2017 11 27. PMCID: PMC5703845 PMID: 29180759
Lu, J., C. Liu, P. Wang, M. Ghazwani, J. Xu, Y. Huang, X. Ma, P. Zhang, and S. Li, "The self-assembling camptothecin-tocopherol prodrug: An effective approach for formulating camptothecin.", Biomaterials, vol. 62, pp. 176-87, 2015 Sep. PMCID: PMC4470812 PMID: 26057133
Lu, J., W. Zhao, H. Liu, R. Marquez, Y. Huang, Y. Zhang, J. Li, W. Xie, R. Venkataramanan, L. Xu, et al., "An improved D-α-tocopherol-based nanocarrier for targeted delivery of doxorubicin with reversal of multidrug resistance.", J Control Release, vol. 196, pp. 272-86, 2014 Dec 28. PMCID: PMC4267990 PMID: 25456831
Lu, J., W. Zhao, Y. Huang, H. Liu, R. Marquez, R. B. Gibbs, J. Li, R. Venkataramanan, L. Xu, S. Li, et al., "Targeted delivery of Doxorubicin by folic acid-decorated dual functional nanocarrier.", Mol Pharm, vol. 11, issue 11, pp. 4164-78, 2014 Nov 03. PMCID: PMC4224520 PMID: 25265550
Lu, J., Y. Huang, W. Zhao, R. T. Marquez, X. Meng, J. Li, X. Gao, R. Venkataramanan, Z. Wang, and S. Li, "PEG-derivatized embelin as a nanomicellar carrier for delivery of paclitaxel to breast and prostate cancers.", Biomaterials, vol. 34, issue 5, pp. 1591-600, 2013 Feb. PMCID: PMC3529003 PMID: 23182923
Lu, J., Y. Huang, W. Zhao, Y. Chen, J. Li, X. Gao, R. Venkataramanan, and S. Li, "Design and characterization of PEG-derivatized vitamin E as a nanomicellar formulation for delivery of paclitaxel.", Mol Pharm, vol. 10, issue 8, pp. 2880-90, 2013 Aug 05. PMCID: PMC3778165 PMID: 23768151
Huang, Y., J. Lu, X. Gao, J. Li, W. Zhao, M. Sun, D. Beer Stolz, R. Venkataramanan, L. Cencia Rohan, and S. Li, "PEG-derivatized embelin as a dual functional carrier for the delivery of paclitaxel.", Bioconjug Chem, vol. 23, issue 7, pp. 1443-51, 2012 Jul 18. PMCID: PMC3399921 PMID: 22681537