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Zheng, K.W., He, Y.D., Liu, H.H., Li, X.M., Hao, Y.H. and Tan, Z. (2017) Superhelicity Constrains a Localized and R-Loop-Dependent Formation of G-Quadruplexes at the Upstream Region of Transcription. ACS Chem. Biol., 12, 2609-2618. Zhao, Y., Zhang, J.Y., Zhang, Z.Y., Tong, T.J., Hao, Y.H. and Tan, Z. (2017) Real-Time Detection Reveals Responsive Cotranscriptional Formation of Persistent Intramolecular DNA and Intermolecular DNA:RNA Hybrid G-Quadruplexes Stabilized by R-Loop. Anal. Chem., 89, 6036-6042. Li, X.M., Zheng, K.W., Hao, Y.H. and Tan, Z. (2016) Exceptionally Selective and Tunable Sensing of Guanine Derivatives and Analogues by Structural Complementation in a G-Quadruplex. Angew. Chem. Int. Ed. Engl., 55, 13759-13764. Liu, H.h., Zheng, K.w., He, Y.d., Chen, Q., Hao, Y.h. and Tan, Z. (2016) RNA G-quadruplex formation in defined sequence in living cells detected by bimolecular fluorescence complementation. Chem. Sci., 7, 4573-4581. Li, X.M., Zheng, K.W., Zhang, J.Y., Liu, H.H., He, Y.D., Yuan, B.F., Hao, Y.H. and Tan, Z. (2015) Guanine-vacancy-bearing G-quadruplexes responsive to guanine derivatives. Proc. Natl. Acad. Sci. USA, 112, 14581-14586. Liu, J.Q., Xiao, S., Hao, Y.H. and Tan, Z. (2015) Strand-Biased Formation of G-Quadruplexes in DNA Duplexes Transcribed with T7 RNA Polymerase. Angew. Chem. Int. Ed. Engl., 54, 8992-8996. Wu, R.Y., Zheng, K.W., Zhang, J.Y., Hao, Y.H. and Tan, Z. (2015) Formation of DNA:RNA Hybrid G-Quadruplex in Bacterial Cells and Its Dominance over the Intramolecular DNA G-Quadruplex in Mediating Transcription Termination. Angew. Chem. Int. Ed. Engl., 54, 2447-2451. Tan, Z., Tang, J., Kan, Z.Y. and Hao, Y.H. (2015) Telomere G-Quadruplex as a Potential Target to Accelerate Telomere Shortening by Expanding the Incomplete End-Replication of Telomere DNA. Curr. Top. Med. Chem., 15, 1940-1946. Xiao, S., Zhang, J.Y., Wu, J., Wu, R.Y., Xia, Y., Zheng, K.W., Hao, Y.H., Zhou, X. and Tan, Z. (2014) Formation of DNA:RNA Hybrid G-Quadruplexes of Two G-Quartet Layers in Transcription: Expansion of the Prevalence and Diversity of G-Quadruplexes in Genomes. Angew. Chem. Int. Ed. Engl., 53, 13110-13114. Zheng, K.W., Wu, R.Y., He, Y.D., Xiao, S., Zhang, J.Y., Liu, J.Q., Hao, Y.H. and Tan, Z. (2014) A competitive formation of DNA:RNA hybrid G-quadruplex is responsible to the mitochondrial transcription termination at the DNA replication priming site. Nucleic Acids Res., 42, 10832-10844. Zhang, J.Y., Zheng, K.W., Xiao, S., Hao, Y.H. and Tan, Z. (2014) Mechanism and Manipulation of DNA:RNA Hybrid G-Quadruplex Formation in Transcription of G-Rich DNA. J. Am. Chem. Soc., 136, 1381-1390. Zheng, K.W., Xiao, S., Liu, J.Q., Zhang, J.Y., Hao, Y.H. and Tan, Z. (2013) Co-transcriptional formation of DNA:RNA hybrid G-quadruplex and potential function as constitutional cis element for transcription control. Nucleic Acids Res., 41, 5533-5541. Zhang, C., Liu, H.H., Zheng, K.W., Hao, Y.H. and Tan, Z. (2013) DNA G-quadruplex formation in response to remote downstream transcription activity: long-range sensing and signal transducing in DNA double helix. Nucleic Acids Res., 41, 7144-7152. Xiao, S., Zhang, J.Y., Zheng, K.W., Hao, Y.H. and Tan, Z. (2013) Bioinformatic analysis reveals an evolutional selection for DNA:RNA hybrid G-quadruplex structures as putative transcription regulatory elements in warm-blooded animals. Nucleic Acids Res., 41, 10379-10390. Wang, F., Tang, M.L., Zeng, Z.X., Wu, R.Y., Xue, Y., Hao, Y.H., Pang, D.W., Zhao, Y. and Tan, Z. (2012) Telomere- and telomerase-interacting protein that unfolds telomere G-quadruplex and promotes telomere extension in mammalian cells. Proc. Natl. Acad. Sci. USA, 109, 20413-20418. Xue, Y., Liu, J.Q., Zheng, K.W., Kan, Z.Y., Hao, Y.H. and Tan, Z. (2011) Kinetic and Thermodynamic Control of G-Quadruplex Folding. Angew. Chem. Int. Ed., 50, 8046-8050. Wang, Q., Liu, J.Q., Chen, Z., Zheng, K.W., Chen, C.Y., Hao, Y.H. and Tan, Z. (2011) G-quadruplex formation at the 3' end of telomere DNA inhibits its extension by telomerase, polymerase and unwinding by helicase. Nucleic Acids Res., 39, 6229-6237. Chen, C.Y., Wang, Q., Liu, J.Q., Hao, Y.H. and Tan, Z. (2011) Contribution of Telomere G-Quadruplex Stabilization to the Inhibition of Telomerase-Mediated Telomere Extension by Chemical Ligands. J. Am. Chem. Soc., 133, 15036-15044.
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