Xi, Jun - Drexel University - Department of Chemistry

个人简介

PhD, Cornell University, 2002

研究领域

All biological events, such as cell signaling and gene regulation are accomplished by biomacromolecular complexes. I am interested in dissecting these complexes to develop a fundamental understanding of the formation and regulation of these biological machineries. Such studies are critical to the success of identifying drug targets and developing potential therapeutics.

近期论文

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Interaction between the T4 Helicase Loading Protein (gp59) and the DNA Polymerase (gp43): Unlocking of the gp59-gp43-DNA Complex to Initiate Assembly of A Fully Functional Replisome. (2005) Biochemistry 44, 7747-56. Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly. (2005) Biochemistry 44, 2305-2318.