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个人简介

Dr. ir. Eirini Velliou graduated from the National Technical University of Athens (NTUA) Greece in 2006 with a master in Chemical Engineering. Directly after her graduation she worked as a Research Engineer in the Laboratory of Food Chemistry and Technology of the School of Chemical Engineering of NTUA, in the research group of Prof. Petros Taoukis mainly focusing on : (1) designing and validating novel Time Temperature Integrators for the chill chain management of food systems (2) studying microbial and enzymatic inactivation with High Hydrostatic Pressure Technology (3) studying the design of nanoemulsions for food systems (4) analysing novel traceability systems. In 2008, Dr. ir. Eirini Velliou joined the Bioprocess Technology and Control Laboratory (BioTeC) of the Department of Chemical Engineering of the University of Leuven (KU Leuven) in Belgium where she worked as a PhD candidate under the supervision of Prof. Jan Van Impe, Prof. Annemie Geeraerd (Division of Mechatronics, Biostatistics and Sensors, KU Leuven) and Prof. Frank Devlieghere (Laboratory of Food Microbiology and Food Preservation, Ghent University, Belgium). Her research area was within the domain of Predictive Microbiology and she conducted hybrid experimental and computational studies for the understanding and further quantification of the heat stress adaptation of pathogenic bacteria after exposure to chaperones, acids and metabolites. Her experimentation started in liquid systems but during her PhD she developed a solid matrix rheologically stable at high temperatures, which enabled the systematic study of the bacterial heat tolerance in a solid(like) environment. She obtained her PhD from BioTeC at the beginning of 2012. Directly after her PhD she joined -as a post-doctoral research engineer- the research group of Prof. Spyros Agathos (Bioengineering Group, GEBI) at the Earth and Life Insitute (ELI) of the Université Catholique de Louvain (UCL) in Louvain-la-Neuve, Belgium. Driven by her passion to understand how biological systems react under the impact of environmental stress she focused on the optimisation of biofuel and carotenoid production from micro-algae under light stress, mechanical stress and nutrient deprivation. In September 2012 she joined -as a post-doctoral research engineer- the research group of Prof. Stratos Pistikopoulos at the Centre for Process Systems Engineerng (CPSE) of the Department of Chemical Engineering of Imperial College London. At Imperial College she worked jointly in CPSE and the group of Prof. Sakis Mantalaris at the Biological Systems Engineering Laboratory (BSEL) focusing on (blood) stem cell and leukaemic cell bioengineering under the impact of environmental (oxidative and metabolic) and chemical (exposure to chemotherapeutic agents) stress in 2D and 3D culture systems. The overall goal of her work was to unravel the impact of environmental stress on the resistance of leukaemia to chemotherapy. Dr. ir. Eirini Velliou was appointed Lecturer at the Department of Chemical and Process Engineering of the University of Surrey in September 2014.

研究领域

Dr ir. Eirini Velliou is founder and principal investigator of the Bioprocess and Biochemical Engineering Group (BioProChem) at the Department of Chemical Engineering. Her research interests fall within the field of bio-processing with particular focus on the impact of environmental stress in a variety of biological systems: Cancer cell bioengineering/tissue engineering under: (1) environmental stress (2) irradiation (3) chemotherapy Stem cell bioengineering in 3D matrices Bacterial resistance and emerging technologies Resistance of stress adapted pathogenic bacteria in host organisms Optimisation of biofuel production from micro-algae: cultivation under environmental stress

近期论文

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Matta-Domjan, B., King. A., Ajaz, M., Matta, C., Lewis, R., Macedo, H., La Ragione, R., Velliou E., Dalton, A. (2015) Carbon Nanotubes: A promising tissue engineering approach for in vitro cultivation and differentiation of primary canine articular chondrocyte. BMC-Musculoskeletal disorders, 15(Suppl 1):S20. Fuentes Gari, M., Misener, R., Garzia-Munzer, D., Velliou, E., M. Georgiadis, M. Kostoglou, Pistikopoulos, E.N., Panoskaltsis, N., Mantalaris, A. (2015) A mathematical model of sub-population kinetics for the deconvolution of leukaemia heterogeneity. Journal of the Royal Society Inerface, volume 12, 2015. Fuentes Gari, M., Velliou, E., Misener, R., Pefani, E., Rende, M., Panoskaltsis, N., Mantalaris, A., Pistikopoulos, E.N. (2015) A systematic framework for the design, simulation and optimization of personalised healthcare: making and healing blood. Computers and Chemical Engineering, 81, 80-93. Velliou, E., Brito Dos Santos, S., M., Papathanasiou, M., Fuentes-Gari, M., Misener, R., Panoskaltsis, N., Pistikopoulos, E.N., Mantalaris, A. (2015) Towards unravelling the kinetics of an acute myeloid leukaemia model system under oxidative and starvation stress: a comparison between two- and three-dimensional cultures. Bioprocess and Biosystems Engineering, 38(8), 1589-1600. Li, J., Stamato, M., Velliou, E., Jeffryes C., Agathos, S.N. (2015) Design, characterization and cultivation of microalgae in an airlift flat panel photobioreactor. Journal of Applied Phycology, 27, 75-86. Trokanas, N., Bussemaker, M., Velliou, E., Tokos, H., Cecelija F. (2015) BiOnto: An ontology for biomass and biorefining technologies. Computer Aided Chemical Engineering, 37, 959.

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