McLean, Samantha - University of Bradford

个人简介

BSc (Hons) First Class in Pharmacology, 2006, University of Leeds PhD in Psychopharmacology, 2010, University of Bradford Preclinical Certificate in Psychopharmacology, 2010, British Association of Psychopharmacology Postgraduate Certificate of Higher Education Practice, 2013, University of Bradford 2010-2011: Post-doctoral research associate, B-neuro, University of Bradford 2011- present: Lecturer in Pharmacology, School of Pharmacy, University of Bradford

研究领域

Cognition, Schizophrenia, Alzheimer's disease, neurodegeneration, animal models

近期论文

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McLean SL, Harte MK, Neill JC, Young AMJ. A preliminary study into the role of prefrontal dopamine in sub-chronic PCP-induced disruption of a cognitive task in the female rat. (In Preparation) McLean SL, Harte MK, Marsh S, Jones GA, Woolley ML, Neill JC. Deficits in gamma oscillations and parvalbumin immunoreactive cell density in the CA3 region of the rat hippocampus following sub-chronic phencyclidine treatment. (In Preparation) McLean SL, Grayson B, Marsh S, Zarroug SHO, Harte MK, Neill JC (2016). Nicotinic α7 and α4β2 agonists enhance the formation and retrieval of recognition memory: Potential mechanisms for cognitive performance enhancement in neurological and psychiatric disorders. Behavioural Brain Research, 302: 73–80 McLean SL, Blenkinsopp A, Bennett MI (2013). Using haloperidol as an anti-emetic in palliative care: informing practice through evidence from cancer treatment and post-operative contexts. Journal of Pain and Palliative Care Pharmacotherapy, 27: 132-5 McLean SL, Idris NF, Gendle DF, Grayson B, Lesage AS, Pemberton DJ, Neill JC (2012). PNU-120596, a positive allosteric modulator of α7 nicotinic acetylcholine receptors, improves a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats. Journal of Psychopharmacology, 26: 1265-1270 McLean SL, Grayson B, Idris NF, Lesage AS, Pemberton DJ, Mackie C, Neill JC (2011). Activation of α7 nicotinic receptors improves phencyclidine-induced deficits in cognitive tasks in rats: implications for therapy for cognitive dysfunction in schizophrenia. European Neuropsychopharmacology, 21: 333-343 Snigdha S, Neill JC, McLean SL, Shemar GK, Cruise L, Shahid M, Henry B (2010). Phencyclidine (PCP)-induced disruption in cognitive performance is gender-specific and associated with a reduction in brain-derived neurotrophic factor (BDNF) in specific regions of the female rat brain. Journal of Molecular Neuroscience, 43: 337-345 McLean SL, Neill JC, Idris NF, Marston HM, Wong EHF, Shahid M (2010). Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat. Behavioural Brain Research, 214: 240-247 Neill JC, Barnes S, Cook S, Grayson B, Idris NF, McLean SL, Snigdha S, Rajagopal L, Harte M (2010). Animal models of cognitive dysfunction and negative symptoms of schizophrenia: focus on NMDA receptor antagonism. Pharmacology and Therapeutics, 128: 419-432 McLean SL, Woolley ML, Neill JC (2010). Effects of sub-chronic phencyclidine on behaviour of female rats on the elevated plus maze and open field. Journal of Psychopharmacology, 24: 787-790 McLean SL, Grayson B, Harris M, Protheroe C, Bate S, Woolley ML, Neill JC (2010). Isolation rearing impairs novel object recognition and attentional set shifting performance in female rats. Journal of Psychopharmacology, 24: 57-63 McLean SL, Woolley ML, Thomas D, Neill JC (2009). Role of 5-HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat. Psychopharmacology (Berl), 206: 403-414 McLean SL, Woolley ML, Neill JC (2009). D1-like receptor activation improves PCP-induced cognitive deficits in animal models: implications for mechanisms of improved cognitive function in schizophrenia. European Neuropsychopharmacology, 19: 440-450 McLean SL, Beck JP, Woolley ML, Neill JC (2008). A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats. Behavioural Brain Research, 189: 152-158