个人简介
河南省特聘教授,享受国务院特殊津贴专家;有机化学重点学科学术带头人,绿色化学介质与反应教育部重点实验室副主任;河南省高校科技创新团队带头人,教育部“长江学者和创新团队发展计划”创新团队带头人;荣获全国优秀科技工作者,河南省劳动模范、河南省优秀专家、学术技术带头人等荣誉称号;国家基础科学人才培养基金评审专家,国际科技合作计划评价专家。
学习与工作经历
1982,09-1986,07 吉林大学化学系,有机化学专业理学学士学位
1986,09-1989,07 吉林大学理论化学研究所、物理化学理学硕士学位。导师:裘祖文教授
1989,07-1992,07 河南师范大学化学系,助教
1992,07-1994,11 河南师范大学化学系,讲师
1994,11-1999,11 河南师范大学化学系,副教授
1999,09-至今 河南师范大学化学与环境科学学院,教授
1999,09-2002,07 北京大学药学院,天然药物与仿生药物国家重点实验室, 药物化学专业理学博士学位。导师:张礼和院士
2003,01―2003,07 美国俄亥俄州立大学生物学院生物化学系,博士后研究员
2003,07―2006,01 美国俄亥俄州立大学生物学院生物化学系,高级研究员
2006,01―至今 河南师范大学化学化工学院,教授、河南省特聘教授、博士生导师
近期论文
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LingjunLi,RanLi,AnlianZhu,GuishengZhang,LiheZhang,CuBr-NCS-mediatedazide-alkynecycloaddition:mildandeffientsynthesisof5-bromo-1,4-disubstituted-1,2,3-triazoles,Synlett,2011,6,874-878.
XiaoyunDang,QingfengLiu,FenglingCui,LixiaQin,GuishengZhang*,XiaojunYao,JuanDu,Animprovedsyntheticapproachto7-[3-amino-4-O-(α-l-mycarosyl)-2,3,6-trideoxy-α-l-lyxo-hexopyranosyl]daunorubicinoneanditsinteractionwithhumanserumalbumin.CarbohydrateResearch,2011,346,949-955.
JianpingLi,JikuanJiu,HuijuanLi,GuishengZhang,Anefficientthree-componentone-potpreparationof1,4-dihydropyridinescontainingnovelsubstitutedpyrazoleundersulfamicacidcatalysis.Chin.J.Chem.,2011,29,511-514.
YanLu,JuanLv,GuishengZhang,GongkeWang,QingfengLiu,InteractionofananthracyclinedisaccharidewithctDNA:Investigationbyspectroscopictechniqueandmodelingstudies.SpectrochimicaActaPartA,2010,75,1511-1515.
XiaopengZhang,HuanzhiJingandGuishengZhang,Selenium-catalyzedoxidativecarbonylationofanilineandalcoholstoN-phenylcarbamates.Synth.Commun.,2010,40,1614-1624.
YanLu,QingqinFeng,FenglingCui,WeiweiXing,GuishengZhang,*XiaojunYao.Interactionof3`-azido-3`-deaminodaunorubicinwithhumanserumalbumin:Investigationbyfluorescencespectroscopyandmolecularmodelingmethods.Bioorg.Med.Chem.,2010,20(23),6899-6904.
HaimingGuo,ZhijieMao,ARKIVOC,2010(ix)300-307.HongyingNiu,DongchaoWang,GuishengZhangandGuirongQu,Improvedone-potsynthesisof6-methylpurinesundermicrowaveirradiation.
ZhiguoHu,*XiaoshanFan,GuishengZhang,Synthesisandcharacterizationofglucose-graftedbiodegradableamphiphilicglycopolymersP(AGE-glucose)-b-PLA.Carbohydr.Polym.,2010,79,119-124.
LingjunLi,JiuxiaWang,GuishengZhang*,QingfengLiu,Amildcopper-mediatedGlaser-typecouplingreactionunderthenovelCuI/NBS/DIPEApromotingsystem,TetrahedronLett.,2009,50,4033.
FenglingCui,XiaoduoKong,LixiaQin,GuishengZhang*,QingfengLiu,BeileiLei,XiaojunYao,Specificinteractionof4′-O-(a-l-Cladinosyl)daunorubicinwithhumanserumalbumin:ThebindingsiteIIonHSAmolecularusingspectroscopyandmodeling,J.Photochem.Photobio.B,2009,95(3),162-169.
FenglingCui,LixiaQin,GuishengZhang,*XiaojunYao,BeileiLei,StudyoftheInteractionofAglyconofDaunorubicinwithHumanSerumAlbuminbySpectroscopyandModeling,MacromolBiosci,2008,8,1079-1089.
FenglingCui,LixiaQin,GuishengZhang,*QingfengLiu,XiaojunYao,BeileiLei,Interactionofanthracyclinedisaccharidewithhumanserumalbumin:Investigationbyfluorescencespectroscopictechniqueandmodelingstudies,J.Pharma.Biomed.Anal.,2008,48,1029-1036.
FenglingCui,LixiaQin,GuishengZhang,*XiaobingLiu,XiaojunYao,BeileiLei,Aconciseapproachto1,11-didechloro-6-methyl-4`-O-demethylrebeccamycinanditsbindingtohumanserumalbumin:Fluorescencespectroscopyandmolecularmodelingmethod,Bioorg.Med.Chem.,2008,16,7615-7621.
LingjunLi,GuishengZhang,*AnlianZhuandLiheZhang,Aconvenientpreparationof5-Iodo-1,4-disubstituted-1,2,3-triazole:multi-componentone-potreactionofazideandalkynemediatedbyCuI-NBS,J.Org.Chem.,2008,73(9),3630-3633.
LeiShi,GuishengZhang*andFengPan,Fe2(SO4)3·xH2O-catalyzedper-O-acetylationofsugarscompatiblewithacid-labileprotectinggroupsadoptedincarbohydratechemistry,Tetrahedron,2008,64,2572-2575.
FenglingCui,LixiaQin,GuishengZhang,XiaojunYao,JuanDu,Bindingofdaunorubicintohumanserumalbuminusingmolecularmodelinganditsanalyticalapplication.Int.J.Biol.Macromol.,2008,42,221-228.
GuishengZhang*,QingfengLiu,LeiShi,JiuxiaWang,Ferricsulfatehydrate-catalyzedO-glycosylationusingglycolswithorwithoutmicrowaveirradiation,Tetrahedron,2008,64,339-344.
GuishengZhangandQingfengLiu.Ferricsulphatehydrate-catalyzed,microwave-assistedsynthesisof2,3-unsaturatedO-glycosidesviatheFerrierreaction.Synth.Commun.,2007,37,3485-3492.
GuishengZhang,*LeiShi,QingfengLiu,J.Wang,L.LiandX.Liu.Adivergentstrategyforconstructingasugarlibrarycontaining2,6-dideoxysugarsanduncommonsugarswith4-substitution.Tetrahedron,2007,63,9705-9711.
G.Zhang,L.Shi,Q.Liu,X.Liu,L.LiandJ.Wang,Adivergentapproachto3-azido-2,3,6-trideoxy-L-hexosesfromrhamnal,TetrahedronLett.,2007,48,3413-3416