Thirty-three compounds were isolated from Gelsemium elegans. Among them, compound 16 was a new natural product and its absolute configuration was elucidated by spectral analysis and an esterification reaction. Compounds 14, 17, 24, 25, 26, 29, 30, and 32 were isolated from this plant for the first time. Compounds 1–23 were screened for their in vitro inhibitory activities against the human breast cancer cell line MCF-7 and mouse hepatocellular carcinoma cell line Hepa 1-6. The results showed 1, 13, 14 and the total alkaloids had different inhibitory activities against the cancer cell lines previously mentioned.

中文翻译：

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Gelsemium elegans 的化合物及其抗癌活性

从 Gelsemium elegans 中分离出 33 种化合物。其中，化合物 16 是一种新的天然产物，其绝对构型通过光谱分析和酯化反应阐明。化合物 14 、 17 、 24 、 25 、 26 、 29 、 30 和 32 首次从该植物中分离出来。筛选化合物 1-23 对人乳腺癌细胞系 MCF-7 和小鼠肝细胞癌细胞系 Hepa 1-6 的体外抑制活性。结果显示 1 、 13 、 14 和总生物碱对前面提到的癌细胞系具有不同的抑制活性。