Cardiovascular disease is one of the main causes of mortality worldwide. Andrographolide represents an important category of natural phytochemicals that has significant therapeutic potential in various conditions such as acute lung injury, heart disease, and viral infections due to its anti-oxidative, anti-inflammatory, and anti-apoptotic properties. This compound plays a protective role in human pathophysiology. This review provides a comprehensive overview of the effects of andrographolide on cardiovascular disease and examines its essential roles and mechanisms in cardiovascular disease and other vascular dysfunctions. The data collected in this review serve as a comprehensive reference for the role of andrographolide in cardiovascular disease and provide valuable insights for further research and the development of andrographolide as a novel therapeutic approach for cardiovascular disease.

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穿心莲内酯及其衍生物在心血管疾病中的综合评价

心血管疾病是全世界死亡的主要原因之一。穿心莲内酯代表了一类重要的天然植物化学物质，由于其抗氧化、抗炎和抗凋亡特性，在急性肺损伤、心脏病和病毒感染等各种情况下具有重要的治疗潜力。这种化合物在人类病理生理学中起保护作用。本综述全面概述了穿心莲内酯对心血管疾病的影响，并探讨了其在心血管疾病和其他血管功能障碍中的重要作用和机制。本综述中收集的数据可作为穿心莲内酯在心血管疾病中作用的综合参考，并为穿心莲内酯作为心血管疾病新治疗方法的进一步研究和开发提供有价值的见解。